BLOOMFIELD, N.J., Feb. 27 /PRNewswire-FirstCall/ -- Alfacell Corporation (Nasdaq: ACEL - News) today announced that the full enrollment target of 316 patients has been reached for the international, confirmatory Phase IIIb registration trial evaluating ONCONASE® (ranpirnase), the Company's lead investigational drug candidate, as a treatment for unresectable malignant mesothelioma (UMM).
The Company has developed and managed one of the largest UMM clinical programs ever undertaken. Over 600 UMM patients have been enrolled in the ONCONASE UMM study, including newly-diagnosed and refractory patients treated with ONCONASE as a single agent and in combination with doxorubicin.
"We are pleased to have achieved this important milestone ahead of schedule, and look forward to completion of all other regulatory requirements for the marketing approval of ONCONASE in the U.S., E.U. and other markets," stated Kuslima Shogen, Chief Executive Officer of Alfacell.
ONCONASE is being evaluated at over 40 investigator sites across 10 countries in a centrally-randomized, open-label Phase IIIb trial as a treatment for UMM, an asbestos-related cancer that afflicts approximately 10,000 people worldwide -- including 4,000 in the U.S. -- each year. The study is being conducted to determine whether survival is prolonged in UMM patients treated with ONCONASE in combination with doxorubicin compared to doxorubicin alone. The estimated global UMM market is $300 million.
ONCONASE is a first-in-class therapeutic from Alfacell's proprietary ribonuclease (RNase) technology platform. ONCONASE has been shown to target tumor cells while sparing normal cells. ONCONASE is internalized by endocytosis and released into the cytosol of the cancerous cell, where it selectively degrades tRNA beyond repair. In doing so, ONCONASE inhibits protein synthesis, stops cell cycle proliferation, and induces apoptosis (programmed cell death).
ONCONASE has previously been granted Orphan Drug designation from EMEA and TGA (Australia), as well as Fast Track status by the FDA. The latter has enabled the Company to complete and submit sections of the New Drug Application (NDA) on an accelerated, rolling basis.
In addition to the Phase IIIb UMM registration trial, the Company is conducting an ONCONASE Phase I / II trial in Non-Small Cell Lung Cancer (NSCLC). The NSCLC market is expected to exceed $4 billion by 2012.
Also, pre-clinical studies examining ONCONASE conjugates as potential treatments for gliomas and Non-Hodgkins Lymphoma (NHL) are being conducted at Johns Hopkins University and the National Cancer Institute (NCI), respectively.
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GRIPPER PLUS(R) Safety Huber Needles are used to deliver medications intravenously through a patient's implanted port. Their unique feature is a safety arm that is lifted to lock the needle into a protected position when de-accessing it from an implanted port. An audible click provides clinicians with confirmation that the de-accessed needle is in its locked safety position. With the addition of a needleless access site, GRIPPER PLUS(R) Safety Huber Needles continue to be an important part of an organization's needlestick safety program.
Smiths Medical has sold millions of GRIPPER PLUS(R) Safety Huber Needles since their launch in 2002.
Smiths Medical is a world leader in the design, manufacture, and distribution of medical devices used in infusion therapy, including CADD(R) ambulatory infusion pumps, PORT-A-CATH(R) implantable access systems, GRIPPER PLUS(R) safety huber needles, CliniCath(R) PICC infusion catheters, and the CozMore(R) insulin technology system. Headquartered in St. Paul, MN, Smiths Medical MD (Medication Delivery) is part of Smiths Group, London, and is committed to developing the highest quality, most reliable products to provide innovative, convenient and cost-effective drug delivery worldwide. For more information, visit www.smiths-medical.com or call 1-800-426-2448.
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Public release date: 14-Mar-2006 - Many cases of environment-related mesothelioma have been reported in the Cappadocia region or Anatolian plateau of Turkey. Blocks of erionite from volcanic tuff have been used in construction, and storage rooms for produce have been cut in the tuff. Past reports have suggested that erionite exposure may increase the risk of mesothelioma, and studies have shown that erionite is associated with a higher risk of cancer development in animals than any other fiber previously tested.
Y. Izzettin Baris, M.D., of Hacettepe University in Ankara, Turkey, and colleagues followed 891 men and women age 20 years and older in three villages in Turkey two exposed to erionite, one control for 23 years. During this period, 372 deaths occurred, and 119 of these deaths occurred from mesothelioma. This form of cancer mainly affects the lining of the lung and was the cause of 44.5% of all deaths in the two villages with erionite exposure. Only two cases of mesothelioma occurred in the control village, both in people born outside of the control village.
The mortality data were analyzed jointly with Philippe Grandjean, M.D., Ph.D., of the Harvard School of Public Health. When standardized to the world population, the annual incidence of pleural mesothelioma in the two exposed villages was 200 and 700 cases per 100,000 people annually, compared to a rate of 10 cases per 100,000 people each year in the control village. The authors conclude that the long-term exposure to erionite is the cause of the exceedingly high risk of developing mesothelioma.
"Our results emphasize the severity of the mesothelioma endemic in erionite-exposed areas of Turkey," the authors write. They add, "In the rural part of central Anatolia, Turkey, millions of inhibitants are likely exposed to hazardous amounts of mineral fibers from the environment. Resources should therefore be directed to preventing these environmental exposures and additional study of the association between environmental exposure to nonasbestos fibers and the risk of cancer."
Contact: Christina Roache, Office of Communications, Harvard School of Public Health, 617-432-6052, croache@hsph.harvard.edu
Citation: Baris YI and Grandjean P. Prospective Study of Mesothelioma Mortality in Turkish Villages With Exposure to Fibrous Zeolite. J Natl Cancer Inst 2006; 98: 414-417.
Note: The Journal of the National Cancer Institute is published by Oxford University Press and is not affiliated with the National Cancer Institute. Attribution to the Journal of the National Cancer Institute is requested in all news coverage. Visit the Journal online at http://jncicancerspectrum.oxfordjournals.org/.
Contact: Ariel Whitworth
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
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Food Allergy Expert Reacts to McDonald's News of Allergens in Cooking OilDr. Ellen Cutler is concerned about the hidden allergins in fast food and feels that parents need to know what their kids are eating.
San Francisco, CA (PRWEB) March 15, 2006 -- After years of misinformation to the public about their fries being free of allergens, McDonalds has recently disclosed that the very oil they cook the fries in has allergens in the form of derivatives of dairy, wheat and gluten in it. Allergy specialist, Dr. Ellen Cutler announced today that she has some deep concerns about the publics health and their absolute need to know about the ingredients in their food.
Dr. Cutler is the author of the Food Allergy Cure and says that the ingredients in McDonalds frying oil can cause severe allergic reaction to many and children are the most vulnerable. Even the slightest hint of wheat, for example, can cause highly allergic symptoms such as fatigue, asthma, rashes, ADD symptoms, as well as all the myriad of digestive distress such as heartburn, bloating and irritable bowel, she said.
Dairy can also cause a severe allergic reaction for some people and is very common in autistic children and children with ADHD, Just a little bit of dairy can create severe setbacks, she added. Sometimes even a little bit of dairy can cause asthma, severe digestive symptoms, and anaphylactic reaction in individuals and this is especially true for children.
Ellen Cutler, DC, MD has written three books on the prevention and treatment of allergies, obesity and chronic health problems, including Winning the War Against Asthma and Allergies, Winning the War Against Immune Disorders and Allergies and The Food Allergy Cure. Her latest work is reflected in her latest book MicroMiracles, Discover the Healing Power of Enzymes (Rodale Press, September 2005). She is available for interviews on this topic. For media interviews call Connie St John, The St John Group, 415-454-2243.
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Merck executive acknowledges pressure to bring Vioxx to market
Winston-Salem Journal - Winston-Salem,NC,USA
calculated in the 1990s that it would lose $611 million in sales if it failed to develop its Vioxx painkiller before a rival introduced a similar product, the ...Merck accused of rushing Vioxx
New Zealand Herald - New Zealand
Drug company Merck & Co accelerated development of its Vioxx pain reliever because it calculated it could lose more than US$600 million ($925.49 million) a ...Vioxx plaintiff admits files don't reflect his claim
OregonLive.com - Portland,OR,USA
SAN FRANCISCO -- The city of Santa Clara, Calif., agreed to pay Enron Corp. creditors $36.5 million to settle a lawsuit over terminated ...
Merck Defends Vioxx as 'One of Most-Studied' Drugs as Latest Trial ...
Insurance Journal - USA
insisted at the start of another Vioxx trial that the company adequately investigated the drug's safety and asserted it was heart disease and other ailments ...
Merck rushed Vioxx development, court told
Reuters - USA
By Jon Hurdle. ATLANTIC CITY, NJ, March 7 (Reuters) - Merck & Co. Inc. (MRK.N: Quote, Profile, Research) accelerated development of its Vioxx pain drug because ...
Merck accused of withholding Vioxx facts
NewKerala.com - Ernakulam,Kerala,India
ATLANTIC CITY, NJ: A trial is under way in Atlantic City, NJ, in which pharmaceutical maker Merck & Co. is accused of withholding Vioxx safety information. ...
Plaintiff takes stand, describes heart attack he blames on Vioxx
East Valley Tribune - Mesa,AZ,USA
ATLANTIC CITY, NJ -A man who blames Vioxx for his heart attack took the stand in his lawsuit against Merck & Co. on Friday, acknowledging ...Merck rushed Vioxx development, court told
Reuters - USA
... accelerated development of its Vioxx pain drug because it calculated it could lose more than $600 million a year if it did not beat competitors to market, a ...
Jury Sees Merck Documents in Vioxx Case
CBS News - USA
(AP) A jury hearing a Vioxx product liability case got its first look Tuesday at e-mail messages, internal documents and other materials showing manufacturer ..._______________________________________________________
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United Therapeutics Ovarian Cancer Drug Closer to CommercializationLeading Canadian scientist gets behind new ovarian cancer drug as United Therapeutics conducts Phase III trials in more than 60 research centers across the U.S. New biotech drug, with a reported benign safety profile, may extend ovarian cancer patients life by 22 months.
SARASOTA, FL (PRWEB) March 14, 2006 -- Dr. Lorne Tyrrell, Chief Executive of ViRexx Medical (AMEX: REX; Toronto: VIR), told StockInterview, This is a study where the drug has been given fast track approval and orphan drug status. Dr. Tyrrell referred to the Phase III clinical trials now being conducted for his companys monoclonal antibody OvaRex MAb. A subsidiary of United Therapeutics (NASDAQ: UTHR), which has licensed OvaRex from ViRexx Medical is testing the ovarian cancer drug on more than 300 late-stage ovarian cancer patients in more than 60 research centers across the U.S.
According to Dr. Tyrrell, OvaRex had been tested in Canada prior to the current testing, There have been a number of patients that have received OvaRex. Weve had no adverse effects from these patients. Dr. Tyrrell is on sabbatical from the University of Alberta, as professor or medical microbiology and immunology, to ensure OvaRex MAb continues advancing through the current clinical studies and into the marketplace.
Will OvaRex MAb cure ovarian cancer? Dr. Tyrrell told StockInterview, In most cases, it will be a delay (of death). We hope that one day we will be able to cure this disease. This has the potential to be an important step at helping to stimulate immune response to achieve a better outcome. Hopefully, one day we can improve that to where it is a cure. Said Chief Executive of United Therapeutics Martine Rothblatt, It is our hope that OvaRex will help women and their physicians combat this disease.
Market Outlook Journal
Dr. Tyrrell is featured in StockInterviews Market Outlook Journal, which can be viewed in its entirety at http://www.stockinterview.com/journal.html
About ViRexx Medical
ViRexx Medical Corp. (AMEX: REX; Toronto: VIR) is a biotechnology company, which develops therapeutic products for the treatment of chronic Hepatitis B, Hepatitis C, other infectious diseases, and selected solid tumors. The companys lead product OvaRex MAb is currently undergoing Phase III clinical trials through a subsidiary of United Therapeutics.
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Maxwell Releases MedConferencelive 2.0Software upgrade delivers increased functionality, flexibility and interactivity of online medical, pharma and biotech events.
Philadelphia, PA (PRWEB) March 14, 2006 The Maxwell Group, provider of the only web conferencing platform developed specifically for delivery of live, online brand product promotion and medical education programs, will release the Medconferencelive 2.0 software upgrade today.
Maxwells proprietary Medconferencelive platform set the standard for live, online web conferencing events in 2003 and 2004. Delivering more than 6000 events in 2005, feature-rich Medconferencelive offers a full range of interactivity including: private and public chat, whiteboards, interactive surveys, audience polling and exit surveys. The 2.0 Release enhances the tools functionality with streaming audio, streaming video, indexing of slides, customizable links, and attendance tracking. It also boosts event flexibility with the ability to upload presenter slides, speaker photos and other images on the fly.
Medconferencelive 2.0 enables todays healthcare organization to stay competitive in the current marketplace, say James Miller, Maxwells Director of Sales. As product managers seek out efficient and cost-effective ways to deliver strategic communications to the medical industry, Medconferencelive 2.0 simplifies the realities of presenting, participating in and viewing live, OnDemand and podcasted events.
Differentiating Live 2.0 from off-the-shelf competitors is the platforms extensive branding capabilities, which incorporate client logos and colors; speaker photos, talk titles and biographies; links to product web sites; custom client links; and custom forms and surveys to deliver fully-branded pharmaceutical, biotechnology and other healthcare communication programs to groups of 250 or more.
Also unique to Maxwells platform, Live and Live 2.0 are built in the Macromedia Flash environment allowing for seamless, autonomous operation within the Flash Player readily available from more than 98% of personal computers in use today.
Events delivered by Medconferencelive 2.0 are seamlessly integrated with Maxwells Medconference Manager servicea hosted, fully-secure, web-enabled event management solution that administers all phases of event production, from scheduling to event marketing, to registration and confirmation services, to technical event support and facilitation to data collection and reportingand is available on a pay-per-event model requiring no up-front capital investment.
For more information about Medconferencelive 2.0 or The Maxwell Group, visit www.themaxwellgroupinc.com.
About The Maxwell Group
The Maxwell Group is the leading provider of live web conferencing solutions to Fortune 1,000 companies. Founded in 1989, The Maxwell Group is a pioneer in the field of online events, eLearning webcasts, web conferencing and Podcasting, offering a comprehensive menu of pre-event, live-event and post-event services.
The Maxwell Group manages more live, direct-to-physician, web conferencing events than any other company in the world. This year, the company will conduct more than 6,000 events, reaching some 300,000 physicians around the world. Through MedConferenceLive, the companys proprietary web conferencing platform, The Maxwell Group offers the only fully-integrated web conferencing technology and support service package specifically designed to assist pharmaceutical companies in brand promotion, speaker training, advisory board meetings, clinical investigator training and more.
MedConferenceLive improves physician access and time to market in a convenient and flexible format providing pharmaceutical companies a distinct competitive edge.
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Healthcare Research Tool Consolidates 12 Months of Industry Data on Searchable CD-ROMA new searchable electronic resource compiled by the Healthcare Intelligence Network (HIN) places the latest healthcare statistics, facts and figures from 2005 research studies at the fingertips of industry professionals. The Healthcare Daily Data Bytes 2006, a keyword-searchable database on CD-ROM, is aimed at healthcare professionals researching new projects, writing reports and compiling presentations. This resource allows users to get the healthcare statistics and figures they need from the leading healthcare consulting firms, think tanks and research and government institutionswithout having to wade through periodicals, journals and other documents or conduct Internet searches for that one piece of necessary data.
Manasquan, NJ (PRWEB) March 14, 2006 -- A new searchable electronic resource compiled by the Healthcare Intelligence Network (HIN) places the latest healthcare statistics, facts and figures from 2005 research studies at the fingertips of industry professionals. The Healthcare Daily Data Bytes 2006, a keyword-searchable database on CD-ROM, is aimed at healthcare professionals researching new projects, writing reports and compiling presentations.
This resource allows users to get the healthcare statistics and figures they need from the leading healthcare consulting firms, think tanks and research and government institutionswithout having to wade through periodicals, journals and other documents or conduct Internet searches for that one piece of necessary data. For more information, please visit http://www.hin.com/cgi-local/link/news/pl.cgi?databytepr.
Compiled each business day in 2005 from the most current research available, each of the more than 250 Data Bytes on the CD-ROM contains an abstract of a newly announced healthcare research study, a link to the original study source and a related resource. Users can conduct instant keyword searches on the latest findings in consumer-driven healthcare, disease management, e-health, wellness, Medicare, Medicaid, pay-for-performance, and many other areas. Search results are returned by relevancy and can be printed for easy reference.
According to Melanie Matthews, HIN executive vice president and chief operating officer, the Healthcare Daily Data Bytes 2006, Keyword Searchable CD-ROM is drawn from the Data Bytes that HIN publishes each business day for its clients in the healthcare industry. So often industry professionals are seeking that one statistic to back up a proposal or budget request or complete a research effort, Matthews states. The Healthcare Daily Data Bytes 2006 facilitates these tasks by putting a years worth of current studies in one electronic tool. In the time that it takes to hit the Enter" key, the information appears on the users computer screen. With one more keystroke, it can be saved to a file or sent to a computer printer.
The 2006 edition of Healthcare Daily Data Bytes contains statistics on hundreds of topics, including the following:
* Cost of Chronic Health Conditions;
* Employers Adopting Health Management, Consumer-Directed Programs to Control Costs;
* Growth of Consumer-Driven Healthcare Plans;
* Impact of Medicare Payment Cuts;
* Most Popular Form of Health Insurance;
* Pay-for-Performance Results Show Improvements in Healthcare;
* Performance Gap Narrows Between Successful Medical Groups and Others;
* Quality Report Cards: Improves Ability to Identify Best Providers by Racial Minorities;
* Survey Sheds Light on Key Regional Health Information Organizations Benefits and Issues; and
* Women's Health in the United States Shows Patterns by State for Key Indicators.
In addition to these studies, the CD-ROM contains more than 200 other relevant findings. For more information, please visit http://www.hin.com/cgi-local/link/news/pl.cgi?databytepr.
About the Healthcare Intelligence NetworkHIN is the premier advisory service for executives seeking high-quality strategic information on the business of healthcare. For more information, contact the Healthcare Intelligence Network, PO Box 1442, Wall Township, NJ 07719-1442, (888) 446-3530, fax (732) 292-3073 or visit http://www.hin.com.
Contact:
Patricia Donovan
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Vicious Cycle Disorders Discovered as Cause of Unresolved Symptoms With New Home Health TestMillions of Americans dont feel well while their medical tests indicate their health is okay. Yet they continue to suffer from symptoms that fail to respond to conventional forms of treatment. A Vicious Cycle Disorder may be the reason.
Virginia Beach, VA (PRWEB) March 14, 2006 - Many are suffering needlessly from unresolved symptoms and don't know what to do. Not feeling well is not normal, but now there's an answer.
Dr. Richard DiCenso has identified the experience of constant unresolved symptoms as a Vicious Cycle Disorder (VCD). This experience is distinguished by chronic, low grade symptoms with no apparent cause that concern an individual and interfere with his or her enjoyment of life.
If you suffer from aches, pains, and ailments that fail to respond to conventional forms of treatment; if the medications you are taking are making you tired because they only temporarily mask your symptoms and fail to address the underlying cause of your ailments; if you have undergone countless tests and exams only to find your results fall within normal limits indicating that youre healthy when you know youre not, a Vicious Cycle Disorder (VCD) may be the cause.
Theres always a reason behind every health situation, he said. The challenge is to find the reason, and its not always obvious through normal medical testing. Now there's a way to find the cause of a VCD (vicious cycle disorder).
Dr. DiCenso recently developed the Matrix Assessment Profile (MAP), a two-part testing program, which is administered in the home. The results of our testing and subsequent follow-up have been literally amazing, Dr. DiCenso noted. Ninety per cent of the people who submit to this testing get ninety per cent of their results within ninety days, regardless of the presenting symptoms.
With credentials in both the conventional and complementary care arenas, Dr. DiCenso is recognized as a leading authority in "Whole Person Therapy." He details the causes of Vicious Cycle Disorders (VCD) in his new book, "Beyond Medicine, exploring a new way of thinking" and offers suggestions for turning your symptoms into solutions.
Dr. DiCenso maintains an active practice as the Clinical Director of Advanced Therapeutics in Virginia Beach, VA.You can obtain a free copy of his new report on Vicious Cycle Disorders (VCD) called Why You Feel The Way You Do And What You Can Do About It, at his website at http://www.MatrixTransformation.com.
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Kinder, Gentler ChemotherapyWith the advent of technology brought to the U.S. from France, having to postpone, even stop, regular life activities to go to a chemo ward to receive chemotherapy treatments, may be a thing of the past. Utilizing a portable, computerized pump that can fit in a fanny pack, patients receive their chemotherapy at a time when it will be most effective and least toxic.
Evanston, IL (PRWEB) March 13, 2006 -- With the advent of technology brought to the U.S. from France, having to postpone, even stop, regular life activities to go to a chemo ward to receive chemotherapy treatments, may be a thing of the past. Utilizing a portable, computerized pump that can fit in a fanny pack, patients receive their chemotherapy at a time when it will be most effective and least toxic.
"Using a portable, computerized pump to deliver chemotherapy allows patients to participate in normal daily activities such as walking, jogging, yoga, and even sleeping while they are receiving their treatments," states cancer specialist Keith Block, MD, who brought this technology to the U.S, and is a member of the National Cancer Institutes PDQ Cancer CAM Editorial Board. This unique pump allows for a more specialized method of chemotherapy administration than just modifying the timing of the drug alone. This revolutionary delivery system has demonstrated in large randomized trials its potential to improve survival."
One patient, LisaAnn McConnell, used to go in-line skating along Lake Michigan wearing that special fanny pack. Little did anyone know that the fanny pack she wore was administering chemotherapy for her colon cancer.
"It allows for larger doses to be delivered more frequently, with higher efficacy and lower toxicity," said pioneering chronobiologist Dr. William Hrushesky, a senior clinical investigator at the Dorn VA Medical Center in South Carolina, one of just a handful of U.S. locations that offers chronotherapy. "It's kinder, gentler and at the same time, more aggressive and effective."
"Every drug has an optimal time when it is least toxic and most effective," says Dr. Block. "For cancer treatment, this is determined by several factors, including the biological uniqueness of the particular drug being given, the time when the specific type of cancer cells divide the most, when the normal healthy cells of the patient generally divide the least, the patients circadian clock and individual rest-activity cycles, and even the time zone the person resides in."
"We have found that often patients receiving their chemotherapy this way reduce what would have been recurring side effects of nausea, vomiting, diarrhea, and fatigue," explained Dr. Block cofounder and Medical/Scientific Director of the Block Center for Integrative Cancer Care, and Director of Integrative Medicine Program at the University of Illinois College of Medicine at Chicago. This is important because the debilitation caused by chemo can cause patients to reduce or even stop treatments that could otherwise help them win their battle with cancer." In fact, current research shows that up to 1/3 of chemotherapy patients abandon treatments prematurely due to the side effects.
According to Dr. Block, "Even after prior treatments have failed patients, using our specialized pumps to administer chronomodulated chemotherapy, we have been able to re-challenge these same patients with the identical drug regimen and this time around gotten successful results."
McConnell, who was diagnosed with colon cancer at age 46, is the third generation in her family to have been diagnosed with this form of cancer, and until now there have been no survivors. Im happy to say that my doctors now think that my cancer is 100% gone, says McConnell, now 47.
The Block Center for Integrative Cancer Care located in Evanston, Illinois, was founded in 1980 by Penny and Keith Block, M.D., committed to the unrelenting belief that no cancer patient should ever be given up on, and with a focus on treating the patient as a whole person, not simply treating the diagnosis. The Center's research-based treatment integrates an innovative approach to the best of conventional medicine with scientifically sound complementary therapies -- therapeutic nutrition, botanical and phytonutrient supplementation, prescriptive exercise, and systematic mind-body strategies, to enhance the recovery process. Block has pioneered this "middle ground" approach to cancer care and optimal health -- designing a total treatment plan that is tailored to the precise needs of each patient, using a unique set of clinical and laboratory assessments. The Block Center is breaking new ground with the creation and development of Cancer Rehab as an innovative treatment modality, and is currently the only private North American medical center using chronomodulated chemotherapy. Dr .Block is a member of the National Cancer Institutes PDQ Cancer Complementary and Alternative Medicine (CAM) Editorial Board in Washington, D.C. While the Block Center is a full treatment clinic, it is also officially a CCOP site through the National Cancer Institute, and is engaged in clinical cancer research with the University of Illinois and other university facilities in the United States and Israel (www.blockmd.com)
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Seventh US Patent Issued to Analytical Spectral Devices, Inc. Related to Verification of PharmaceuticalsAnalytical Spectral Devices, Inc. (ASD), manufacturer of precision analytical instruments for real-time, field based material identification and verification, announced today that the United States Patent and Trademark Office has issued Patent Number 7,006,214 related to ASDs innovative solution, RxSpec® technology.
Boulder, Colo., March 10, 2006 Analytical Spectral Devices, Inc. (ASD), manufacturer of precision analytical instruments for real-time, field based material identification and verification, announced today that the United States Patent and Trademark Office has issued Patent Number 7,006,214 related to ASDs innovative solution, RxSpec® technology.
This is ASDs seventh patent covering pharmaceutical verification and the second patent specifically related to our RxSpec® drug verification solution says Dave Rzasa, President and CEO. These patents further strengthen ASDs leadership position in providing solutions to furthering pharmacist productivity, while at the same time combating counterfeits.
ASDs patented RxSpec® technology utilizes a combined visible and near infrared spectroscopy inspection system to directly check the prescription drug while in the dispensing vial. The real-time measurement is sensitive to chemical composition, color, and dosage level. The measured chemical fingerprint is compared to an extensive known database, thereby providing absolute assurance that the dispensed drug is correct in both type and concentration, regardless of similarity in appearance. In seconds, RxSpec® technology verifies the identity and dosage of a prescription drug dispensed by a pharmacy, thereby reducing potentially harmful filling errors, as well as detecting counterfeit drugs. And because RxSpec® technology is non-destructive, it can be used to inspect 100% of the prescriptions prepared by a pharmacy.
ASD currently has systems installed at two large central fill and mail order pharmacies which have verified several million filled prescriptions very successfully. With the systems currently in operation, combined with the installations at the two new Department of Veterans Affairs Consolidated Mail Outpatient Pharmacies in Chelmsford, Massachusetts and Tucson, Arizona, ASD will continue to grow an already extensive library of unique spectral fingerprints of the most commonly dispensed prescription drugs.
RxSpec® technology is the first real tool to automate the time consuming and labor intensive manual verification process used in virtually every pharmacy. The technology is applicable in all pharmacy environments, including central fill, mail order, retail, and hospital pharmacies, says Dr. Brian Curtiss, Chief Technology Officer. While ASDs current systems have focused on verification of solid dosage pharmaceuticals in high volume pharmacies, ASD has versions of the RxSpec® system in development for a wide range of additional dosage forms, including injectables and IV solutions.
About ASD
Founded in 1990, Analytical Spectral Devices manufactures cost-effective, precision, transportable and field-portable, laboratory-quality Vis/NIR spectrometers, spectroradiometers, spectrophotometers and corresponding software and accessories. ASDs instruments perform well in a range of environmental conditions, in and outside the laboratory, and have applications in pharmaceutical, nutraceutical, analytical chemistry, mining, grain, food and dairy, remote sensing, pulp and paper industries world-wide. For more information, please contact Amanda Griffin, Analytical Spectral Devices, 5335 Sterling Dr., Suite A, Boulder, CO, 80301; 303/444-6522, 303/444-6825 (fax); www.asdi.com.
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Fleeing Doctors Run No More; Pennsylvania Organization, MDS, Says They Have the Solution to the Rampant Malpractice DilemmaA company in Pennsylvania, founded by physicians and attorneys, has developed a solution to the rampant litigation and awards plaguing the medical community. For years, due to unbridled litigation, the threat of litigation and ridiculous judgments and settlements, doctors have been fleeing the areas they are needed the most to avoid persecution. Malpractice Defense Services provides a revolutionary approach to malpractice defense.
Plymouth Meeting, PA (PRWEB) March 13, 2006 -- A company in Pennsylvania, founded by physicians and attorneys, has developed a solution to the rampant litigation and awards plaguing the medical community.
Malpractice Defense Services Home Page
In many states, medical practitioners are being subjected to a high number of frivolous lawsuits that affect the physicians' professional and private lives, as well as their accessibility to patients.
These suits, coupled with the resulting annual bump in medical malpractice premiums, have caused many physicians to flee to other, less dangerous, locations. This is especially the case in states in the Northeast such as Pennsylvania, the location of MDS' headquarters.
"People have been discussing what it would be like if it was difficult, if not impossible, to find a specialist in their own county or even state. Well, it's no longer a matter of 'what if'. Communities are losing great doctors due to the impotence of the current system", says Dr. Todd Morehouse, an ear, nose and throat surgeon and a Director at MDS.
"Unfortunately for the defendants involved in these protracted lawsuits, there is no one who is truly on their side", states attorney Todd Nurick, MDS' President and CEO. "The insurance-appointed attorneys are paid hourly. They are looking out for the best interests of the insurance company, not the doctor, and have no incentive to have the physician removed from the litigation as soon as possible."
Why is this?
"It's the result of what we call the 'Triple Threat'. The insurance company pays the insurance-appointed attorneys bill;
Its the insurance companys money at stake in a settlement or judgment; and,
The insurance company directs the attorneys actions.
The real client is the insurance company."
Seemingly, then, the doctors have no one looking out for them, making sure that their voice is heard.
Morehouse agrees, stating that, "Clearly, the current method for protecting yourself, as a practitioner, is not sufficient. This has resulted in higher judgments, higher settlements and longer litigation. Thats why premiums are increasing again in 2006."
"Most medical practitioners have been forced to hire private counsel to augment the insurance-appointed counsel in malpractice litigation. That can cost from $10,000 to $40,000 or more", says Morehouse.
Both Nurick and Morehouse are confident that MDS is the solution to what they claim is a plague, especially in the Northeast.
Dr. Morehouse states, "MDS is a 'revolutionary approach to malpractice defense'."
"MDS is a retainer-based organization that was created to be more-than-affordable to the medical community. We provide the doctors with the highest level of malpractice defense. No more need to go running around trying to find an attorney at the last minute and shelling out perhaps tens of thousands of dollars at once. MDS is not there just before or at the beginning of litigation, but throughout the entire process."
MDS not only provides the practitioner with preventive information and advice, but will be there the second that doctor is named as a defendant in a lawsuit. We don't just write a few letters threatening to sue back if the doc wins. We actually serve as the client's personal counsel throughout the entire litigation. The 'missing link', if you will", says Nurick.
Unlike other companies Nurick claims are "run by 'profiteers' with the goal of benefiting from the pain of the doctors and their communities, MDS, the 'original', serves as a physician's personal attorney."
And, unlike those other organizations Nurick refers to, MDS does not just write a few letters on the physicians' behalf and refer them to an outside law firm. MDS is committed to being the doctor's private counsel and colleague.
MDS' goal is to get the doctor out of any litigation as soon as possible, without stretching out the process to generate fees for plaintiff attorneys and insurance appointed defense attorneys. "We've found that most of the doctors named are not even targets of the litigation. They're just being named for the sake of greed."
Whose greed?
"We'll leave that to the public to answer. I believe in common sense, and I believe that common sense will eventually prevail. If we do our job the way it should be done, MDS will have a permanent effect on malpractice litigation and premiums", Nurick says.
Additionally, MDS fees may be deductible as a legitimate business expense. Check with your accountant.
About Malpractice Defense Services:
MDS was founded in 2004 by attorneys and physicians with the single goal of protecting physicians in litigation, preventing litigation and protecting the community.
MDS is dedicated to the permanent reduction of malpractice lawsuits, premiums, judgments and settlements via the active monitoring of, and aggressive intervention and participation in, malpractice litigation.
MDS is committed to the highest standards of ethics in law and medicine.
Malpractice Defense Services Home Page
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Ambien Class Action Filed in NY Federal Court: Warnings Needed About Adverse Side EffectsBizarre & Dangerous Behaviors Reported Nationwide Related to Ambien use. It Doesn't Give Some Consumers a Good Night's Sleep But Causes Them to Enter into a Hypnotic State & Drive Cars & Binge Eat Without Any Memory
New York, NY (PRWEB) March 10, 2006 -- The New York Times recently reported that last year some 26.5 million prescriptions of Ambien were filled and the manufacturer made some $2.2 billion in sales for a drug they advertise that will put you asleep, BUT some Ambien users nationwide experience bizarre side effects of sleep walking, sleep eating and memory loss that landed them in Jail, they lost their jobs or they were seriously injured, without any memory of what happened to them. Scientific research confirms that Ambien is a powerful hypnotic that can reel people into sleep walking and sleep eating instead of a good nights sleep.
New York City Attorney Susan Chana Lask filed a class action complaint in the Southern District of New York on March 6, 2006, Case No. 06CIV1762. Ms. Lask interviewed people nationwide and an expert pharmacologist-all confirmed the dangerous side effects of Ambien. Four class representatives relate their experiences in the Complaint of taking Ambien for good nights sleep and waking up only to find themselves in jail, driving cars while in a hypnotic state and binge eating at night where their spouses shoveled food from their mouths. Attorney Susan Chana Lask explains, "The purpose of our lawsuit is to insure Ambien warns consumers and doctors about the adverse side effects of sleep walking and sleep eating because it is unfair to Ambien users to enter this hypnotic state then sleep walk and drive, putting themselves and others in danger. You don't want to be that other person crossing the road when an Ambien user is hypnotically driving towards you. The worst part of those side effects is that these people have absolutely no memory of what happened to them after they took Ambien." The filed complaint is at http://www.appellatebrief.com/ambien.html.
The class representatives range from a housewife in Florida, a Texas woman studying for her CPA, a Lab Technician in New York and a Lieutenant in the US Navy. The Florida housewife ate everything in sight, including raw eggs, uncooked canned vegetables and loaves of bread in one evening, and she did this multiple times. Her husband would find her in the morning with her mouth gorged with food and shovel it out of her mouth. The woman from Texas took Ambien one night and woke up on a cement jail floor the next day only to discover she was arrested for driving her car in a zombie like state and crashing into other parked vehicles. She now faces criminal charges. The Lieutenant had a stellar record with the Navy and a high classified position when she took her Ambien and was arrested the next day for shoplifting DVD's from a store. She also drove while on her "shopping spree". She has no memory of the incident and now faces court martial and the loss of hundreds of thousands of dollars in pension and other work related compensation for DVD's worth some $20--something that makes absolutely no sense. The New York Lab Technician was actually assaulted twice when she took her Ambien and entered into a hypnotic state where she opened her door for a stranger and another time she was found in her car in a hypnotic state. Her life has been devastated from the assault where she has horrific fragmented memories of it.
A PRESS CONFERENCE WILL BE HELD MONDAY, MARCH 13, 2006 at 10 A.M. at the Southern District of New York Courthouse steps at Centre Street, New York City.
Contact:
Susan Chana Lask, Esq.
212-358-5762
917-533-7880
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Bird Flu Almost Ready to Go PandemicScientists discover bird flu virus one gene away from human to human transmission.
(PRWEB) March 8, 2006 -- Scientists have now verified through gene sequencing that the H5N1 virus has been rapidly mutating and evolving towards a strain that will be deadly for humans. Six months ago scientists estimated that the H5N1 virus needed to make about five changes to its gene structure for it to be deadly for humans. Now it requires only one last change.
The present strains of avian influenza (bird flu) are mainly infecting only birds, with only a relatively small number of humans being infected. The reason for the drastic preparations now being made by most countries in the world to protect themselves from this virus is that the H5N1 virus still has a very high mortality rate. It can kill up to 100% of domestic chickens and at present can kill an alarming 55% of people that become infected. If a pandemic occurs from a virus with even one quarter of this mortality rate then the world consequences will be horrendous.
>From the World Health Organization statistics only 190 people have been infected since 2003 with the H5N1 virus and of these 92 have died. Most of these people had some direct contact with infected chickens of some kind. Some inefficient human to human transmission has also occurred in some cases.
It appears that it is inevitable that a bird flu pandemic will eventually occur. Some scientists expect that the last genetic change needed for efficient human to human transmission by the H5N1 virus may occur when migrating birds carrying the H5N1 virus begin their return journey in Spring. (Northern hemisphere). This means that there is a possibility that a pandemic could occur within two months.
The H5N1 bird flu virus has now spread to at least 40 countries around the world. The general unhygienic practices combined with poorly developed health systems in some of these countries will create many opportunities for the last genetic change needed for the H5N1 virus to spread from humans to humans as easily as the common cold. It is likely that this change could occur several times in different countries. If it occurs in an underdeveloped country then there will be little chance of detecting it or stopping it from spreading worldwide.
It is estimated that when the H5N1 virus changes to an efficient human to human strain that it would only take three weeks for human H5N1 virus outbreaks to occur everywhere around the world. Computer models from the Los Alamos laboratory predict that it will only take another three to six weeks for the pandemic to spread completely through a country and reach its peak infection rate. This rapid rate of spreading infection will be due to the international and domestic plane transport system. Since H5N1 has an incubation period of two to ten days then it will be impossible to screen infected but still contagious passengers. Depending on the country it originates in, a contagious and deadly H5N1 virus could be seeded around the world before health authorities are aware that a pandemic has started. The World Health Organization has stated that all health systems in every country will be overwhelmed and infected people will have to be cared for at home.
Apart from the direct consequences of large numbers of infected people dying, a potentially worst catastrophe will also occur. Recent surveys have shown that only 30% to 50 % of workers would show up for work if a pandemic occurred. Combined this with 50% of willing workers being infected and others being quarantined then the workforce will be seriously deleted.
It would be very prudent to expect essential supplies and services of any kind will be in very short supply throughout the main wave of the pandemic. This may occur throughout the whole world at the same time. If you think about the possible nightmare consequences of this then you will realize the importance of stocking up your own personal supplies now. Panic buying will ensure that no stocks will be available when the pandemic begins. There is a series of important items to help protect you from the virus which can be found at http://www.bird-flu-influenza.com.
Us officials are now going state to start telling communities to prepare for a six week quarantine. Ontario is bringing in legislation to fine absentee qualified health workers $100,000 and one jail for each day absent. Australian local councils are all attending government sponsored bird flu workshops. These isolated government actions suggests something may be happening soon.
Information from governments to the public is being suppressed and downplayed to prevent panic. The Australian government will not release information to the public on how to prepare for a pandemic and look after infected family members until a pandemic starts. By then it will be too late to buy stocks and understand what to do. This is not a normal flu.
By Stephen Jones
Biologist and Author of the Bird Flu Survival Guide (www.bird-flu-influenza.com)
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Stop Smoking Hypnosis Download Now AvailableA downloadable version of a successful hypnosis CD to stop smoking is now available at www.EasilyStopSmoking.com at a discounted price for a limited time.
London, UK (PRWEB) March 8, 2006 -- EasilyStopSmoking.com, the most successful stop smoking hypnosis system, announces the availability of a downloadable version of its hypnosis CD to quit smoking at less-than-half of the normal CD price. The price discount is available only for a limited time and can be ordered at http://easilystopsmoking.com/downloadCD.php.
The CD was created by a hypnotherapist named Randy Charach who has been helping people change their lives and quit smoking for over 20 years. He has worked with celebrities like John Travolta, Madonna and Sean Penn. EasilyStopSmoking.com founder and director Martin Popham arranged for the rights to sell the product after he and his wife had both used the product and succeeded with it. It took him less than a week to quit smoking using the hypnosis, when he once smoked 40 cigarettes a day for 18 years.
The stop smoking hypnosis program is just like a session in the office of a hypnotherapist. The site now offers a free audio sample, so potential users can listen and know exactly what to expect from the treatment before purchasing.
The success rate of the program is around 93.2%, which is one of the highest rates of any hypnosis product on the market. There is a money-back guarantee within 60 days for customers who are not completely satisfied.
Many people have tried hypnosis without success, but Martin says that those people should not give up. People are too incredibly busy and stressed these days. Its hard to rush off down to the doctors office and be able to sit and relax enough to go under the spell and achieve success. Our program is one which is designed to be listened to in the evening while in bed or while relaxing in a quiet room, and due to the convenience factor, the success rate is much higher.
The downloadable file is available in MP3 and WMA formats and is available for $37 (approximately £20). Users have access to the download page for 30 days so they may access the file as much as they wish in that time. It will work with Windows Media Player or any other audio or media player and can be burned onto a CD or uploaded in an MP3 player to be used anywhere. The file is just over 30 megabytes in size, so users with a slow internet connection should consider ordering the CD instead (which sells for $77, or approximately £43) and this option now comes with free shipping worldwide.
The low price and quick access to the product through the download will make it more accessible to everyone, Martin said. When you are a smoker, and you really and truly find a way to quit, you want to share it with as many people as possible.
About EasilyStopSmoking.com (www.easilystopsmoking.com)
EasilyStopSmoking.com, based out of London, UK, has used its stop smoking hypnosis program to help nearly 1000 people from all over the world stop smoking in only six months of operation. Company founder and director Martin Popham began sharing the program with others after his personal battle with smoking was successful after using the treatment. New features on the site include an audio sample and the availability of both MP3 and WMA files.
Contact:
Martin Popham
Founder and director
07890 803858
http://www.easilystopsmoking.com
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New Guide Facilitates Partnerships between Hospitals, Public Libraries to Inform Consumers About Patient SafetyA new tool is now available to help organizations develop and provide consumer awareness programming for patient safety. Partnering for Patient Empowerment Through Community Awareness (PPECA), a hospital-library collaborative program, is releasing new content this week. The PPECA Facilitators Guide and module presentations are now freely available for organizations to use in their own patient safety educational efforts.
CHICAGO (PRWEB) March 8, 2006 -- National Patient Safety Awareness Week is about promoting the importance of partnership with patients to reduce medical error.
To support other national efforts, Partnering for Patient Empowerment Through Community Awareness (PPECA), a hospital-library collaborative program, is releasing new content this week. The PPECA Facilitators Guide and module presentations are now freely available. The modules and guide will provide direction on presenting a patient safety program that hospitals and libraries can host together to increase awareness among consumers about patient safety.
"We felt it was important to participate in a program that shared information on how patients could become proactive partners in their own safe care," stated Carolyn Anthony, Director of Skokie Public Library, one of the PPECA library participants. Roxanne Goeltz, co-founder of Consumers Advancing Patient Safety (CAPS) and consumer speaker on patient safety agreed: Patients must prepare themselves to be more involved in their healthcare. The atmosphere and resources available at the public libraries partnered with the knowledge and dedication of the hospitals will strengthen the safety net for all patients.
To develop the PPECA model, five northern Illinois hospitals and public libraries worked together to refine content and the program development process. The free Facilitators Guide shares that expertise so others can initiate similar adult education sessions that feature health care practitioners, librarians and consumers as speakers. Program planners who need additional content for their sessions can access streaming video of the presentations from the project Web site at http://www.galter.northwestern.edu/PPECA/index.htm.
PPECA is the first model for building patient safety awareness through participatory community partnerships involving a public library and a healthcare institution. Public libraries have a history of providing educational programs on topics of interest to their communities, says Linda Walton, associate director, Galter Health Sciences Library and PPECA principal investigator. Many people feel more comfortable in a public library environment than in a hospital setting for learning.
The educational sessions include three short presentations designed to raise consumer awareness of:
The consumers role in working with healthcare providers to manage risk of avoidable patient injury;
Patient-centered clinical and systems-based approaches to patient safety; and
Effective medical information gathering to support safe care.
PPECA was developed in collaboration with Consumers Advancing Patient Safety, the Health Learning Center of Northwestern Memorial Hospital, Zipperer Project Management and the Metropolitan Library System. The program has been funded in whole or in part with federal funds from the National Library of Medicine, National Institutes of Health, under Contract. No. NO1-LM-1-3513.
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Medical Doctor Exposes Secrets on How to Avoid Becoming Victim to the Healthcare SystemOvercoming powerful forces that influence the way a patient is treated within the healthcare system is discussed in a recently published book.
Salem, OR (PRWEB) March 8, 2006 -- In this recently published book, Secrets of Medical Decision Making, (ISBN 1932690174, January 2006,) Oleg I. Reznik, M.D. brings to light exactly how a physicians recommendations can be influenced by powerful forces that have nothing to do with the patients best interest. Fear of litigation is one of these forces with power to change the way medicine is practiced, claims Reznik.
A recent report in JAMA (2005; 293) revealed that nearly all (93%) physicians, in six specialties, surveyed reported practicing defensive medicine. The report further states that most physicians avoid procedures and patients that were perceived to elevate the probability of litigation. Furthermore, nearly half of them reported that they had taken steps to restrict their practice by eliminating procedures prone to complications, such as trauma surgery, and avoiding patients who had complex medical problems or were perceived as litigious.
The influence of the pharmaceutical industry on creating medical guidelines is another force responsible for the direction of todays medicine. The current medical model, which was created close to one hundred years ago mainly for the treatment of the acute illnesses, and is now applied to our current plaguechronic illness, explains Reznik. Financial and time pressure is another challenge that is contributing more and more to what happens to the quality of out interaction with a physician, as our health care dollars are dwindling. Speaking about his book, Reznik continues, while the existence of these challenges has been recognized before, I believe that Ive made a contribution in clarifying exactly how they translate into the everyday doctor-patient interaction.
Awareness of the factors that go into medical decision making will always help to find a better solution to any given medical problem. The patient can learn the limiting aspects of the physicians and of their own thinking that lead to more suffering. Physicians, bound by their own fears and pressures, are one such source of such suffering. Patients unreasonable expectations are another. The audience should be aware every time they see a commercial advertising a medication or a medical service on TV, that such advertising does not have purely altruistic motives. For this reason it is biased, prone to inaccuracies and to giving false impressions. Our false impressions about the capabilities of medicine drive us to its unnecessary consumption, to disappointment, frustration, resentment, to emotional and physical pain, claims Reznik.
While modern medicine does have an effective arsenal of treatments for the acute medical problems, things are different when it comes to chronic illness. A modest slowing of progression is the most modern medicine can boast, when it comes to most chronic illness. In my book I accurately describe what medicine can and cannot do for some of the common medical problems. It is my hope awareness of these issues would motivate the reader/listener to take charge of their own lives and consider their health in the light of their own lifestyles, instead of believing that someone else (the medical system) will fix it for them, reiterates Reznik. I wrote this book to bring a sense of independence and self-empowerment to the prospective patients. During my training and practice as a physician I became acutely aware of the great deal of suffering that stems not only from the illnesses, but more so from the beliefs that most people have regarding the capabilities of the modern medical system. These beliefs almost invariably lead to disappointment, frustration, and a great deal of physical and emotional pain. Patients with such beliefs submit themselves to tests and invasive procedures that bring them nothing more than additional suffering.
Oleg I. Reznik, M.D., practices almost exclusively mind-body medicine in his private practice, while continuing to do conventional medicine, hospital work, and low-risk obstetrics at Willamette Family Medical Center in Salem, Oregon. Secrets of Medical Decision Making: How to Avoid Becoming a Victim of the Healthcare Machine, published by Loving Healing Press, is available through online bookstores or may be purchased at a local bookstore. Loving Healing Press books are distributed by Ingram, Baker & Taylor, and New Leaf Distributing. For a review copy, contact email protected from spam bots
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FLAVORx Develops Innovative Solution for HIV and AIDS Children -- Company Reaches Out to Children in Thailand and the Dominican RepublicFLAVORx Inc has recently wrapped up studies to provide palatable solutions to combat the bitter taste of antiretroviral HIV and AIDS medications. Because taste plays a crucial role in medicinal compliance, the design of a liquid medication that children can actually swallow allows these young patients to receive the live-saving treatment they need. Due to its success with patients in Thailand and the Dominican Republic, FLAVORx has submitted the manuscript to the CDC, the Clinton Foundation and the Clinical Infectious Diseases Journal.
Bethesda, MD (PRWEB) March 7, 2006 -- FLAVORx, Inc, the company that sets the gold standard in developing scientifically tested medicinal flavorings has expanded its pharmaceutical repertoire to include antiretroviral medications used to treat patients with HIV and AIDS. The company will use its proprietary taste masking agents to improve the existing taste of these medications to increase adherence to drugs and, as a result of improved treatment, lengthen lives. According to Doctors Without Borders, an international medical humanitarian organization, efforts to treat children with HIV and AIDS are hampered by foul-tasting medications. Regardless of a childs obedience or willingness, in some cases the intolerable taste of a medication will illicit a biological and uncontrollable response that forces rejection of the medication. Many children that are HIV positive do not understand why they must endure a horrible tasting medication when they dont feel bad. Alternatively, caretakers realize the importance of a life-saving antiretroviral medication but find it extremely difficult to administer to children. This illustrates the point that taste alone can impede a child from receiving treatment necessary for his/her survival.
The World Health Organization estimated that at the end of 2005, 2.3 million children around the world were living with HIV. Of the 3.1 million people who died of AIDS last year, over half a million were children aged below 15 years. These statistics are a sobering reflection of the impact of HIV and AIDS on young lives. During 2005, it is estimated that 700,000 children globally were newly infected with HIV. More than 80% of infections occurred in Africa, with countries in Asia and the Caribbean also seeing an increase in HIV infection numbers among children. Sadly, global child mortality rates show that 25% of newborns infected with HIV die before the age of one, up to 60% die before reaching their second birthday, and most die before they hit the age of five. However, as reported by the United Nations Program on HIV/AIDS, these numbers are markedly different in higher-income countries, with children having access to a wide range of treatment options and often surviving into adulthood. Accordingly, with the proper treatment and resources available in lower-income countries, the world may be able to avoid high rates of infection and death. Critical medications are essential to health and survival.
Zidovudine (Retrovir), an antiretroviral medication manufactured by both GSK (GlaxoSmithKline) and Cipla Pharmaceuticals, was the first drug approved to treat HIV infection, and is commonly recommended for treatment of symptomatic children. The taste is regarded as bitter and metallic, unbearable to the point that some actually stop taking the medication. The consequences of this non-compliance can be life-threatening.
Children have up to 10 times the amount of taste buds as adults, making them much more sensitive to bitter tastes. As reported by Duke University doctors Susan Schiffman and Jennifer Zervakis, the reason why patients fail to take life saving drugs as prescribed may largely be attributed to taste.
The HIV-Netherlands Amsterdam Thailand Research Collaboration recently completed clinical trials with FLAVORx on major antiretroviral medications used for pediatric treatment in Thailand. With each medication and flavor combination tested for safety and effectiveness, FLAVORx developed successful formulations to mask the taste of antiretroviral medications. The results were extremely positive, said Kenny Kramm, CEO of FLAVORx, Inc. We had 100% compliant and much happier pediatric patients who were able to take the proper dosages and follow drug regimens successfully. The manuscripts have been submitted to the CDC, the Clinical Infectious Diseases Journal and the Clinton Foundation for publishing as a recommendation that flavoring be used in all parts of the world to help HIV-infected children live happier, less traumatic lives. The report also asks for assistance to support impoverished countries.
Based on the experience and data collection from Thailand, FLAVORx is currently working on expanded clinical trials in the Dominican Republic before offering its solution to HIV and AIDS afflicted children in all areas of the world. Dr. Consuela Beck-Sague of the Centro de Familia AIDS Clinic in La Romana noted, FLAVORx is used to help alleviate much of the trauma associated with children that are on current HIV-ARV medications. It is a huge help to patients and clinicians.
The FLAVORx FDA-approved flavors and formulary will soon be offered in cooperation with the Clinton Foundation to help children worldwide. If you have worked with children suffering from HIV/AIDS, see how your experience compares to others by taking this short survey: http://www.surveymonkey.com/s.asp?u=64541861562
For more information, please contact Teresa Chen at 800.884.5771, extension 234.
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SpectraSoft Introduces AppointmentsPRO 9 Medical Scheduling SoftwareSpectraSoft officially launches Version 9 of its popular AppointmentsPRO medical scheduling software today. The upgrade offers new features designed to cut patient wait times, improve practice teamwork, simplify paperwork and reduce claim denials. The appointment software is designed for physical therapy practices, medical clinics and hospitals.
Tempe, AZ (PRWEB) March 7, 2006 -- SpectraSoft officially launches Version 9 of its popular AppointmentsPRO medical scheduling software today. AppointmentsPRO 9 offers new features designed to cut patient wait times, improve practice teamwork, simplify paperwork and reduce claim denials. The appointment scheduler is designed for physical therapy practices, medical clinics and hospitals.
The new AppointmentsPRO scheduling system improves office communication with an auto-notification feature that alerts practitioners when a patient has arrived, rescheduled or canceled an appointment. There is also a Task Manager that lets users assign or receive tasks to/from other people in the organization, then monitor the status of each task to ensure critical responsibilities are completed.
Rehab practices will appreciate the expanded patient intake window in AppointmentsPRO 9. It tracks multiple insurance coverages and the number of visits remaining for each authorization. New fields for subscriber, policy number, group number and employer ensure the billing department has all the critical information needed to gain payment for services.
"We set out to create an appointment scheduling system that streamlines workflow throughout a practice to make it more productive and profitable," said Steve Petrie, SpectraSoft's CEO. "I'm very excited with the result. This is not just a front desk [appointment scheduler. It's a communication hub for the entire office and a powerful practice management tool."
AppointmentsPRO 9 includes more than 90 practice management reports, as well as trend reporting with graphs that compare key practice metrics from one month to the next. A new Recall List feature lets you mark patients to be scheduled in the future (i.e. six-month evaluation). Improved security and updated HIPPA compliance make AppointmentsPRO 9 an essential upgrade for any medical practice, rehab clinic or healthcare facility.
In addition to the standard version of AppointmentsPRO 9, there are enhanced versions designed for centralized scheduling, SQL networks and hospital scheduling.
Visit http://www.spectrasoft.com to :
Schedule a call to learn more about AppointmentsPRO 9
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ABOUT SPECTRASOFT
SpectraSoft, Inc. is a leader in simplifying complex appointment-scheduling and documentation tasks for medical practices, physical therapy clinics, hospitals, businesses and government agencies. Founded in 1993, SpectraSoft is located in Tempe, Arizona.
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By Anna Driver
NEW YORK (Reuters) - Opening arguments in the next Vioxx liability trial start on Monday as Merck & Co. (MRK.N: Quote, Profile, Research) faces the lone lawyer who has beaten the company in one of these cases -- this time representing two long-term users of the painkiller who say it caused their heart attacks.
So far, two juries have found Merck not liable, while Mark Lanier, a flamboyant Texas lawyer, helped secure a $253 million judgment for the widow of a Vioxx user last August. The trial, set to begin next week in New Jersey Superior Court in Atlantic City, marks the first involving plaintiffs who took the painkiller for more than 18 months.
Merck withdrew the arthritis drug from the market in September 2004 after a study showed the risk of heart attack and stroke doubled in patients who took Vioxx for at least 18 months. The company, based in Whitehouse, New Jersey, faces nearly 10,000 lawsuits from people accusing it of hiding health risks of a medicine that once generated annual sales of $2.5 billion.
In earlier trials, Merck maintained there was no evidence of heightened risk for short-term Vioxx users. "The length of exposure is a critical issue in these cases," Howard Erichson, a law professor at Seton Hall University, said. "The scientific evidence on causation is stronger for long-term use than short-term use, but that doesn't mean the defendant just lays down."
Lanier is representing Thomas Cona, a 59-year-old New Jersey businessman who says he took Vioxx for 22 months prior to suffering a heart attack in June 2003. The other plaintiff, John McDarby, 77, says he took Vioxx for four years and had a heart attack in April 2004 after a fall in which he also broke his hip.
"I think what you are going to see is that the plaintiffs are going to have a difficult task showing that Vioxx caused their heart attacks," Chuck Harrell, one of Merck's attorneys in Atlantic City, said. "Each of them had multiple pre-existing risk factors that are well known to cause heart attacks." Both men had a history of high blood pressure and high cholesterol and were smokers, Harrell said.
In court documents, Merck, citing prescription records, has also argued that Cona was not even a long-term user of Vioxx.
LANIER FACTOR?
Some even say the outcome of the trial could hinge on the performance of Lanier, a gifted attorney and preacher who has won hundreds of millions of dollars in damages for his clients in product liability cases. "Only one out of four juries was able to reach a conclusion that Merck had withheld important information about Vioxx even though they all received similar factual records," Benjamin Zipursky, a professor at Fordham University School of Law, said.
"One obvious conjecture is that Mr. Lanier has the ability to present these facts in a way that is highly persuasive to the ordinary people sitting on juries," he said. Still, there is some doubt about whether Lanier's folksy Southern style will play in Atlantic City, where an eight-woman and two-man jury was selected to hear the case.
"With trial lawyers, rapport with the jury is very important," Howard Erichson, a law professor at Seton Hall University, said. "An out-of-state lawyer may find it more difficult to connect with a jury, but it's all about preparation."
Merck is based in New Jersey, but its lead attorney in the case is Christy Jones, from the Jackson, Mississippi, firm of Butler, Snow, O'Mara, Stevens & Cannada. The trial is expected to last three to four weeks, an attorney for Merck said.
Fealth.com Unveils Comprehensive Health Search Engine - Vertical Health Search Engine Fealth.com LaunchedFealth.com today unveiled the internets most comprehensive Health Search Engine at http://www.fealth.com. Fealth.com search results provide highly relevant and reliable health information from the vast amount of information available on the Internet. Using industry accepted trust indicators, such as health certifications, to establish high value rankings, Fealth.com filters out irrelevant search results, such as searching for information on a virus though most search engines providing information on computer viruses.
Westlake Village, CA (PRWEB) March 6, 2006 -- Fealth.com today unveiled the Internet's most comprehensive Health Search Engine at http://www.fealth.com. Fealth.com search results provide highly relevant and reliable health information from the vast amount of information available on the Internet. Using industry accepted trust indicators, such as health certifications, to establish high value rankings, Fealth.com filters out irrelevant search results, such as searching for information on a virus though most search engines providing information on computer viruses.
Fealth, derived from fitness and health is available at http://www.fealth.com and is also available for license to internet portals and publishers for integration within their own websites. An initial portal partner, stayhealthy.com which launched in 1995 as one of the first healthcare websites, is using Fealths on-demand and highly customizable search solution to compliment and expand its own health related products.
Fealth is a perfect choice to more than 110 million Internet users who are looking for health information. Cluttered information on the web and lack of a good health search engines cause a significant amount of lost time and effort for any consumer or health care professional. Said Ravi Kalidindi, founder and CEO of Findica Inc, Our search engine provides highly qualified and relevant information without having to page though volumes of irrelevant material.
Fealth is providing us excellent on-demand and highly customizable health search and information solutions. These solutions fit very well into our portal, were easily integrated and give our visitors incredibly qualified information which compliments our own products. said John Collins, CEO of StayHealthy.com We've already received fantastic feedback from our visitors and customers who are finding highly relevant health information that they otherwise would not have found.
About Findica Inc and Fealth
Findica was founded in 2004 with a vision to become a leading provider of industry specific information and search solutions for internet and corporate users. Fealth.com is its first product providing the best health search and navigation experience on the web. Findica is based in Westlake Village, CA, and may be contacted with questions and investment queries via email; or visit our Web site at http://www.fealth.com
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Detroit Attorney Jermaine A. Wyrick Lectures on the Fourth Amendment.Attorney Wyrick Lectures on "Searches" under the Fourth Amendment.
DETROIT, MI (PRWEB) March 4, 2006 -- The Law Offices of Jermaine A. Wyrick P.L.L.C. is pleased to announce that on February 24, 2006, Attorney Jermaine A. Wyrick spoke for Lorman Education Services at the Arrest, Search, and Seizure Seminar on the Fourth Amendment. The subtopics included Search of Persons, Search of Premises, Vehicle and Consent Searches.
Attorney Wyrick has practiced law since 1997. His commitment to helping people is apparent by his chosen areas of practice which include Civil Rights Law, Criminal Defense, Juvenile Law, Personal Injury, and Probate Law.
He is currently a member of the Detroit Metropolitan Bar Association, the State Bar of Michigan, Michigan Trial Lawyers Association, the National Bar Association, and the Board of Directors for the Wolverine Bar Association.
His other civic activities, includes the Coleman A. Young Scholarship Foundation - Board of Directors, Detroit Recovery Project Board of Directors, Detroit Rainbow Push Second Tuesday Network, and the State Bar of Michigan Public Outreach Committee.
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Baxa Automated Pharmacy Production Equipment on Show at the European Association of Hospital Pharmacists CongressUK-based pharmacy products supplier, Baxa Ltd will feature its proprietary systems for automating pharmacy fluid handling and streamlining multi-source mixing applications at the 11th annual Congress of the European Association of Hospital Pharmacists (EAHP) in Geneva from 22nd to 24th March 2006. The EAHP Congress, entitled Quality and Medication Safety Hand in Hand, will focus on quality and safety improvements within the pharmacy and reducing patient risk.
ASCOT, Berkshire (PRWEB) March 3, 2006 -- Baxa Ltd will feature its proprietary systems for automating pharmacy fluid handling and streamlining multi-source mixing applications at the 11th annual Congress of the European Association of Hospital Pharmacists (EAHP) in Geneva from 22nd to 24th March 2006. The EAHP Congress, entitled Quality and Medication Safety Hand in Hand, will focus on quality and safety improvements within the pharmacy and reducing patient risk.
Baxa Corporations innovative approach to product development has produced a succession of leading-edge automated compounders and pumps designed for increased accuracy, safety and efficiency. This includes the state-of-the-art Exacta-Mix 2400 Compounder for multi-source, multi-ingredient compounding such as total parenteral nutrition.
This years EAHP Congress includes the seminar, Production of TPN: evolution over 30 years, a topic for which Baxa has focused both product development and technical support efforts. During the meeting, demonstrations will be available for Baxa automated compounders, as well as the Rapid-Fill Automated Syringe Filler, which automates the process of sterile syringe filling, capping and labeling.
The Congress is being held at the Palexpo Congress Centre, Geneva, Switzerland. Further information can be obtained from http://www.eahponline.org.
About Baxa Corporation
Baxa, a customer-focused medical device company, provides innovative, solution-based technologies for fluid handling and delivery. Its systems and devices promote the safe and efficient preparation, handling, packaging, and administration of fluid medications. Key products include Rapid-Fill??Automated Syringe Fillers, Exacta-Med? Oral Dispensers, MicroFuse? Syringe Infusers, Repeater? Pharmacy Pumps, and Exacta-Mix? and MicroMacro? Multi-Source Compounders; used worldwide in hospitals and healthcare facilities. Privately held, Baxa Corporation has subsidiaries and sales offices in Canada and the United Kingdom; direct representation in Belgium, Denmark, Finland, France, Germany, Luxembourg and The Netherlands; and distribution partners worldwide. Further information is available at http://www.baxa.com.
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Wall Systems Help Create Economical Solution for Cleanrooms at Compounding PharmaciesModular wall systems are a fast and economical solution for Cleanrooms. Porta-King's wall systems meet the new 797 regulations.
ST. LOUIS, MO (PRWEB) March 3, 2006 -- Under the new United States Pharmacopeia (USP) 797 regulation, a cleanroom at a compounding pharmacy or at a pharmaceutical mixing lab must now be in class 10,000. An economical way to incorporate this new regulation is by installing modular cleanrooms by Porta-King.
Gregg Pearlstone, Vice President at Porta-King, notes that prefabricated modular walls and ceiling systems can be a fast and cost-efficient solution for cleanrooms. Porta-King offers four different wall systems that meet the needs of compounding pharmacies.
Porta-Kings modular systems are easy to install, which means that they are much less expensive than the total cost of other cleanroom construction alternatives, Pearlstone said. Our pre-engineered designs can be assembled by people with little or no construction experience. However, if someone needs installation service, we offer a nationwide network of factory authorized contractors who can provide turn-key installation services.
Porta-Kings modular cleanroom walls not only help to create cleaner environments for the compounding process, but can also provide storage for pharmaceutical materials. The modular walls can be customized to accommodate any layout requirements. Filtration systems can also be easily incorporated to create a complete cleanroom package.
Porta-King has been a leader in modular cleanroom systems since 1969. In addition to its modular cleanrooms, Porta-King offers a full line of modular wall systems for a wide variety of other construction applications. In addition, Porta-King manufactures structural steel mezzanines used for storage, production and elevated office space. Porta-King buildings provide shelter and storage solutions for virtually any working environment. For more information, visit www.portaking.com or call 800-284-5346.
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Antiviral Medication Noncompliance During an Avian Flu Pandemic - Deadly Results, If Not For An Easy SolutionAccording to officials, it is not a question of if the avian flu virus will mutate but when? On March 1st, the Centers for Disease Control and Prevention (CDC) issued their recommendation to control the virus with a particular focus on children, the main carrier of the flu. To this end, the US government is procuring millions of doses of Tamiflu® as its first line of defense. However, the pediatric version of this drug has an extremely bitter taste making it not only difficult for children to swallow but to keep down. In response, specialty pharma FLAVORx, Inc has developed four flavors to mask the bitterness and ensure 100% compliance.
Bethesda, MD. (PRWEB) March 2, 2006 -- FLAVORx, Inc has recently concluded testing on its proprietary taste-masking agents in liquid antiviral medications such as Tamiflu®. Combining these flavoring agents with antivirals will safely alleviate the medications existing bitter, unpleasant taste and ensure medicinal adherence for children in the event of an avian flu pandemic. The International Association of Medicinal Compliance (IAMC), a 501(c) (3) non-profit organization dedicated to creating a healthier world through taking medication properly, recognizes the widespread impact on public health as a result of infectious spread in children. Accordingly, a necessity for palatable medication exists not only to eliminate difficulties in swallowing medicines, but more importantly to ensure effectiveness and proper dosing to control the spread of a deadly virus. The IAMC is currently reaching out to government officials to resolve these concerns. To date, the avian flu has rapidly spread across Asia, into Africa and Europe, with seven European countries seeing outbreaks of the virus in birds. With this type of spread the question is not if the avian flu will reach the U.S., but when. Therefore, state and federal government leaders now realize the sense of urgency in planning for a pandemic outbreak and will partner with companies such as FLAVORx to ensure the nations preparedness.
On March 1, 2006, the Centers for Disease Control and Prevention (CDC) issued their recommendation that should the bird flu mutate and affect human beings, spread among American children should be controlled, because viruses are spread through sneezing, coughing and contact, all of which occur with high frequency among children. Several cases of well-documented research support this advisory. In a 1957 flu outbreak in England, over 50% of cases were reported in children. Although many infections occurred in June of that year, the pandemic was not triggered until September, when children returned to school. Additionally, when Japan implemented a flu-control policy derived on the sole vaccination of children, results were markedly similar. During the time of this policy, deaths from pneumonia and flu decreased by numbers of 10,000-12,000 per year, and thus as reported by the New England Journal of Medicine, controlling the spread of flu in children protects the entire population, including the elderly.
As there is currently no approved vaccine in the marketplace, the US government is procuring millions of doses of Tamiflu® as its first line of defense in the event of an avian flu pandemic. The liquid version of this drug will be used to treat children who are not old enough (infants to approximately 8- years old) or have difficulty swallowing pills. The issue of non-compliance among children could prove highly detrimental to all of society. Taking a medication improperly or not completing a full regimen leads to a reduction in symptoms, but does not lead to eradication of an illness. While seemingly inconsequential, not fully ridding the body of infection could lead to children and adults returning to school or the workplace symptom-free but still as viral carriers. Thus the virus will not be completely contained and infection will continue to spread, likely with a more virulent strain that has become partially resistant to a drugs effects, and rendering the original drug and the nations only avian pandemic solution, ineffective.
A childs sense of taste differs vastly from that of an adult. With 10,000 taste buds that rejuvenate themselves every three days (elderly adults have approximately 300 taste buds), children are much more sensitive to bitterness, and therefore unable to tolerate acrid tasting liquid medications that are unpleasant to them. FLAVORx, a company that specializes in taste-masking, has expressly developed four formulations to cover the bitter taste of Tamiflu®, which would prove life-saving in the event of an avian flu outbreak. These formulations have been rigorously tested for safety and stability to ensure that their addition does not affect the medications benefits. Furthermore, studies show that medicinal compliance, and a childs willingness to accept and take medication properly, increased from 53% with the unflavored medication to over 97% with the addition of the medicinal flavoring.
Currently members of Congress such as Congressman Chris Van Hollen are urging states to stockpile pre-formulated FLAVORx flavor packets to be distributed with antiviral medications to ensure safety for the nations citizens. According to Van Hollen, The availability of antivirals, however, will only be effective if flu victims use them in the appropriate manner and doses. Van Hollen further adds, While we all agree that parents have a responsibility to ensure that their children take the required flu doses, pharmacists and others have noted that it can be virtually impossible to get some children to take very bitter medicine. It seems any comprehensive avian flu plan should anticipate this problem and address it appropriately.
To participate and view the latest results on Americans public take on government avian flu preparedness click on http://www.surveymonkey.com/s.asp?u=836251835358. For more information, please contact Gunjan Koul at 240.223.0949.
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Feedback Project Focuses On Patients' NeedsThe Myeloma Institute for Research and Therapy at the University of Arkansas for Medical Sciences (UAMS) launched the Patient Initiated Quality Improvement Project in January, a pilot program designed to improve the quality of clinical care and customer service at the center.
Little Rock, AR (PRWEB) March 1, 2006 -- The Myeloma Institute for Research and Therapy (http://myeloma.uams.edu) at the University of Arkansas for Medical Sciences (UAMS -- http://www.uams.edu) launched the Patient Initiated Quality Improvement Project in January, a pilot program designed to improve the quality of clinical care and customer service at the center.
The six-month project, funded by a grant from the Cynthia and George Mitchell Foundation, involves the analysis of detailed patient feedback by a committee comprised of UAMS staff and Myeloma Institute (http://myeloma.uams.edu) patients. A total of 12 patients are providing the committee with electronic feedback regarding their clinical experiences and other aspects of treatment via e-mail, according to Dr. Elias Anaissie, the Myeloma Institute's director of the Supportive Care Division.
"We've encouraged them to take notes while they are going to their appointments, seeing the nurse, seeing the doctor. We want to hear whatever they have to say, the good, the bad and the ugly," said Anaissie, who is on the committee along with Dr. Charles Smith, UAMS' medical director, and two MIRT patients.
All of the patients' remarks are kept confidential, Anaissie said, adding that certain suggestions have already led to improvements in treatment processes.
"The healthcare system in this country and worldwide is not patient-friendly. We believe that the solution is not going to come from Congress or some think tank but from the patient. Empowering the patient as a partner, rather than a passive recipient of care, has the potential to transform healthcare in a most positive way. Patient issues must be taken into consideration and corrective action must be taken if we are to better serve our patients and improve our efficiency," Anaissie said.
Besides the e-mail responses, the committee is also reviewing feedback forms handed out to patients during their clinic visits as well as written suggestions from those patients undergoing stem cell transplants.
"This idea is where the future of medicine is heading," said Smith, who expects similar projects to be utilized in all UAMS clinics in the near future. "The doctor-patient encounter is becoming demystified. This will provide us with guidance on how the system needs to change and make it more sensitive to patient needs."
About the University of Arkansas for Medical Sciences (UAMS):
UAMS is the state's only comprehensive academic health center, with five colleges, a graduate school, a medical center, five centers of excellence and a statewide network of regional centers. UAMS has about 2,320 students and 690 residents and is one of the state's largest public employers with almost 9,000 employees. UAMS and its affiliates have an economic impact in Arkansas of $4.3 billion a year. UAMS centers of excellence are the Arkansas Cancer Research Center (http://www.acrc.uams.edu), Harvey and Bernice Jones Eye Institute (http://www.uams.edu/jei), Donald W. Reynolds Institute on Aging (http://centeronaging.uams.edu), Myeloma Institute for Research and Therapy (http://myeloma.uams.edu/) and Jackson T. Stephens Spine & Neurosciences Institute (http://www.uams.edu/stephensinstitute).
Contact:
Leslie W. Taylor, 501-686-8998
Wireless phone: 501-951-7260
http://www.uams.edu / http://myeloma.uams.edu
Andrea Peel, 501-686-8996
Wireless phone: 501-351-7903
http://www.uams.edu / http://myeloma.uams.edu
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